Porphyromonas gingivalis OMVs Activate Macrophage-Hepatic Stellate Cells via Thbs1/TGF-β Signalling in NAFLD
Overall, this study verified the correlation between NAFLD and periodontitis and provides novel insights into the vital role of P. gingivalis OMVs in activation of macrophage-hepatic stellate cells through Thbs1/TGF-β signalling pathway in the context of NAFLD and periodontitis.
Authors
- Peng Luo (ORCID: https://orcid.org/0000-0002-8215-2045)
- Zixin Guo (ORCID: https://orcid.org/0000-0002-8005-2630)
- Kai Shi (ORCID: https://orcid.org/0000-0002-9181-5664)
- Pei Yu (ORCID: https://orcid.org/0000-0003-4041-4681)
- Zhe Wu (ORCID: https://orcid.org/0000-0002-3005-6422)
- Congcong Lv
Institutions
- Stomatology Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- International Dental Journal
- Published
- 2025-11-09
- DOI
- https://doi.org/10.1016/j.identj.2025.104005
- Citations
- 2
- Primary Topic
- Liver physiology and pathology
- Type
- article
- Field-Weighted Citation Impact
- 2.64