Experimental Cancer Medicine Centre (ECMC) network proposal for a consensus gene panel for pan-cancer sequencing: a Delphi methodology
This consensus-based gene panel offers a standardised approach to pan-cancer genomic screening. It supports harmonised diagnostics and could improve patient access to personalised therapies and research trials across clinical and NHS settings.
Authors
- Aditi Vedi (ORCID: https://orcid.org/0000-0001-6761-6510)
- Magdalena Meissner (ORCID: https://orcid.org/0000-0001-5897-0219)
- Darren Hargrave (ORCID: https://orcid.org/0000-0001-8219-9807)
- Bristi Basu (ORCID: https://orcid.org/0000-0002-3562-2868)
- Alastair Greystoke (ORCID: https://orcid.org/0000-0001-9168-0387)
- Milind Ronghe (ORCID: https://orcid.org/0000-0002-1865-9335)
- Joanna Zabkiewicz
- Zohra Butt (ORCID: https://orcid.org/0000-0002-8307-9812)
- Harriet S. Walter (ORCID: https://orcid.org/0000-0003-2618-711X)
- Gary Middleton (ORCID: https://orcid.org/0000-0001-5695-3474)
- Andrew D. Beggs (ORCID: https://orcid.org/0000-0003-0784-2967)
- Claire McKeeve
- Patricia Roxburgh (ORCID: https://orcid.org/0000-0001-9869-591X)
- Stefan Nicholas Symeonides (ORCID: https://orcid.org/0000-0002-9892-9314)
- Deborah A. Tweddle (ORCID: https://orcid.org/0000-0003-2208-3970)
- Kienan I. Savage (ORCID: https://orcid.org/0000-0002-4898-899X)
- Robert H. Jones (ORCID: https://orcid.org/0000-0003-3576-9496)
- Brent O’Carrigan (ORCID: https://orcid.org/0000-0001-8187-6298)
- Juanita Suzanne Lopez (ORCID: https://orcid.org/0000-0001-8321-4212)
- Natalie Cook (ORCID: https://orcid.org/0000-0003-2606-1082)
- Simon J. Crabb (ORCID: https://orcid.org/0000-0003-3521-9064)
- Richard Phillips (ORCID: https://orcid.org/0000-0002-8978-9743)
- Eileen E. Parkes (ORCID: https://orcid.org/0000-0002-7855-3698)
- Debashis Sarker (ORCID: https://orcid.org/0000-0003-4814-8429)
- Paul Shaw
- Muhammad Yasin Kureeman
- Mounia Beloueche
Institutions
- Queen's University Belfast (GB)
- Royal Marsden NHS Foundation Trust (GB)
- Boehringer Ingelheim (Germany) (DE)
- Institute of Cancer Research (GB)
- King's College London (GB)
- University of Cambridge (GB)
- Velindre NHS Trust (GB)
- NHS Greater Glasgow and Clyde (GB)
- Royal Hospital for Children (GB)
- University Hospital of Wales (GB)
- University Hospitals of Leicester NHS Trust (GB)
- Cambridge University Hospitals NHS Foundation Trust (GB)
- Edinburgh Cancer Research (GB)
- University of Oxford (GB)
- Pierre Fabre (United Kingdom) (GB)
- The Christie NHS Foundation Trust (GB)
- Cancer Research UK Clinical Trials Unit (GB)
- University of Southampton (GB)
- University College London (GB)
- University of Glasgow (GB)
- University of Birmingham (GB)
- Newcastle University (GB)
Publication Details
- Journal
- British Journal of Cancer
- Published
- 2025-11-08
- DOI
- https://doi.org/10.1038/s41416-025-03252-6
- Primary Topic
- Cancer Genomics and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Cancer Research UK
- National Institute for Health and Care Research
- Imperial Experimental Cancer Medicine Centre