Preoperative Fractionated Stereotactic Radiosurgery for Brain Metastases: A Prospective Pilot Study at a Single Institution

Fractionated preoperative SRS appears to be safe and effective with high rates of local control and low rates of LMD and radionecrosis. Results of ongoing phase 3 studies directly comparing preoperative to postoperative SRS will help further define the appropriate sequencing of therapies.

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Publication Details

Journal
Advances in Radiation Oncology
Published
2025-11-08
DOI
https://doi.org/10.1016/j.adro.2025.101951
Citations
1
Primary Topic
Brain Metastases and Treatment
Type
article
Field-Weighted Citation Impact
1.52
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article

Preoperative Fractionated Stereotactic Radiosurgery for Brain Metastases: A Prospective Pilot Study at a Single Institution

Matthew J. Shepard, Alexander Kwong-Tak Yu, Stephen Karlovits, Alexander S. Marwaha et al.
1 citations
Advances in Radiation Oncology
Brain Metastases and Treatment
1.52
article

Preoperative Fractionated Stereotactic Radiosurgery for Brain Metastases: A Prospective Pilot Study at a Single Institution

Matthew J. Shepard, Alexander Kwong-Tak Yu, Stephen Karlovits, Alexander S. Marwaha, Rodney E. Wegner, Yun Liang
article en
1 citations

Abstract

Fractionated preoperative SRS appears to be safe and effective with high rates of local control and low rates of LMD and radionecrosis. Results of ongoing phase 3 studies directly comparing preoperative to postoperative SRS will help further define the appropriate sequencing of therapies.

Advances in Radiation OncologyVol. 11(2)
Allegheny Health Network (US), Yale New Haven Hospital (US)
Openalex Percentile: Top 13%
Brain Metastases and Treatment
1.52
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