Nicotinic acid protects against hepatic ischemia-reperfusion injury via suppressing mitochondrial damage-induced ferroptosis
NA improves mitochondrial function by promoting mitophagy and mitochondrial biogenesis, which reduces ferroptosis and oxidative stress, thereby alleviating HIRI.
Authors
- Jia Yao (ORCID: https://orcid.org/0000-0003-1457-7241)
- Xiaodan Guan (ORCID: https://orcid.org/0000-0003-3716-4503)
- Xijing Yan (ORCID: https://orcid.org/0000-0001-8406-4287)
- Lijun Zhang (ORCID: https://orcid.org/0000-0002-9372-1004)
- Yina Sun
- Zihan Liu (ORCID: https://orcid.org/0009-0000-4573-9368)
- Ming Lei (ORCID: https://orcid.org/0000-0001-9818-3586)
- Rong Li (ORCID: https://orcid.org/0000-0003-4951-577X)
- Jun Zheng (ORCID: https://orcid.org/0000-0002-0511-458X)
- Qian Zeng (ORCID: https://orcid.org/0000-0002-3909-7386)
- Jiandong Zha
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Sun Yat-sen University (CN)
- Key Laboratory of Guangdong Province (CN)
- University of Hong Kong - Shenzhen Hospital (CN)
- Third Affiliated Hospital of Sun Yat-sen University (CN)
- University of Hong Kong (HK)
Publication Details
- Journal
- Liver Research
- Published
- 2025-11-08
- DOI
- https://doi.org/10.1016/j.livres.2025.11.001
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00