Prevention of microbiological contamination of drugs during their preparation for anaesthesia in the operating theatre: the Non-Touch trial
The Non-Touch method demonstrated consistently low bacterial contamination (<1%) in both laboratory and clinical environments. Moreover, propofol syringe sterility was maintained for ≥6 h post preparation. These findings support further evaluation of Non-Touch as a practical strategy to enhance injection safety in routine anaesthetic and critical care settings.
Authors
- Sebastian Spatz
- Thomas C. Adam (ORCID: https://orcid.org/0000-0001-6146-0260)
- Christine Geffers (ORCID: https://orcid.org/0000-0003-3047-6416)
- Sascha Tafelski (ORCID: https://orcid.org/0000-0002-5623-8400)
- Brar Piening (ORCID: https://orcid.org/0000-0002-4478-5597)
- Rollin Nagel
- Irit Nachtigall (ORCID: https://orcid.org/0000-0002-9976-9295)
- Claudia Spies
- Sebastian Zeuch
Institutions
- Humboldt-Universität zu Berlin (DE)
- Vivantes Klinikum (DE)
- Institut für Hygiene und Umwelt (DE)
- Fraunhofer Institute for Production Systems and Design Technology (DE)
- Berlin University of the Arts (DE)
- Franklin University (US)
- Charité - Universitätsmedizin Berlin (DE)
Publication Details
- Journal
- Journal of Hospital Infection
- Published
- 2025-11-08
- DOI
- https://doi.org/10.1016/j.jhin.2025.10.028
- Primary Topic
- Infection Control in Healthcare
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology
- Deutsche Forschungsgemeinschaft
- Max-Planck-Gesellschaft
- Einstein Stiftung Berlin
- European Society of Anaesthesiology
- Gemeinsame Bundesausschuss
- Robert Koch Institut