CT-guided bone biopsies with non-diagnostic results in pediatric patients—a multi-institutional 10-year retrospective review
Question Limited data exist on the prevalence and outcome of non-diagnostic CT-guided bone biopsy in pediatric patients to guide clinical management. Findings About one-third of CT-guided bone biopsies in pediatric patients were non-diagnostic, though most were ultimately benign. Lesions with non-aggressive features were associated with non-diagnostic results. Clinical relevance In the setting of multidisciplinary care for patients with suspected primary bone tumors, non-diagnostic CT-guided bone biopsy-particularly in lesions with non-aggressive imaging features-strongly favors benignity, which should steer management towards a more conservative approach.
Authors
- Kin Fen Kevin Fung (ORCID: https://orcid.org/0000-0002-2731-2915)
- Yee Ling Elaine Kan (ORCID: https://orcid.org/0000-0002-6839-6000)
- Fei Wan (ORCID: https://orcid.org/0000-0002-8311-5553)
- Pui Kwan Joyce Chan (ORCID: https://orcid.org/0000-0003-3207-5704)
- Amanda Kan
- James Francis Griffith (ORCID: https://orcid.org/0000-0001-5206-9382)
- Stefanie W. Y. Yip (ORCID: https://orcid.org/0000-0002-1050-6975)
- Pak Lun Lam
- Kwok Chuen Wong (ORCID: https://orcid.org/0000-0002-2960-3003)
- Kelly Y. C. Lai (ORCID: https://orcid.org/0000-0001-8623-6089)
Institutions
- Chinese University of Hong Kong (HK)
- Kwong Wah Hospital (CN)
- Kowloon Hospital (CN)
- Duchess of Kent Children's Hospital (CN)
- Queen Elizabeth Hospital (GB)
- Prince of Wales Hospital (CN)
Publication Details
- Journal
- European Radiology
- Published
- 2025-11-08
- DOI
- https://doi.org/10.1007/s00330-025-12128-5
- Primary Topic
- Bone Tumor Diagnosis and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00