Association of leukocyte count with atherosclerotic cardiovascular disease in patients with genetically defined familial hypercholesterolaemia
Higher levels of WBCC, NC and MC are significantly associated with an increased prevalence of ASCVD in patients with HeFH. Targeting inflammation may be a valuable strategy for managing the development and progression of ASCVD in FH.
Authors
- Dick C. Chan (ORCID: https://orcid.org/0000-0001-7658-5197)
- Seyed Saeed Tamehri Zadeh (ORCID: https://orcid.org/0000-0001-7803-5850)
- Jing Pang (ORCID: https://orcid.org/0000-0002-9700-6948)
- Gerald F. Watts
Institutions
- The University of Western Australia (AU)
- Royal Perth Hospital (AU)
Publication Details
- Journal
- Nutrition Metabolism and Cardiovascular Diseases
- Published
- 2025-11-08
- DOI
- https://doi.org/10.1016/j.numecd.2025.104457
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Amgen
- AstraZeneca
- Sanofi
- Regeneron Pharmaceuticals
- Australian Government
- Novo Nordisk
- Esperion Therapeutics
- Medical Research Council
- National Health and Medical Research Council