Characterizing the Paradoxical Interplay of Semantic Perseveration and Derailment in Psychiatry Using Theory-Driven Generative Language Simulations

Integrating density-based metrics with traditional semantic distance measures may better capture FTD symptoms, though further validation in clinical samples is needed. This approach improves understanding of perseveration and its interaction with (dis)organization in thought and speech, with potential clinical applications.

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Publication Details

Journal
Schizophrenia Bulletin
Published
2025-10-28
DOI
https://doi.org/10.1093/schbul/sbaf205
Primary Topic
Mental Health via Writing
Type
article
Field-Weighted Citation Impact
0.00
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article

Characterizing the Paradoxical Interplay of Semantic Perseveration and Derailment in Psychiatry Using Theory-Driven Generative Language Simulations

Robin Quillivic, Raymond J. Dolan, Isaac Fradkin
Schizophrenia Bulletin
Mental Health via Writing
article

Characterizing the Paradoxical Interplay of Semantic Perseveration and Derailment in Psychiatry Using Theory-Driven Generative Language Simulations

Robin Quillivic, Raymond J. Dolan, Isaac Fradkin
article en

Abstract

Integrating density-based metrics with traditional semantic distance measures may better capture FTD symptoms, though further validation in clinical samples is needed. This approach improves understanding of perseveration and its interaction with (dis)organization in thought and speech, with potential clinical applications.

Schizophrenia Bulletin
Wellcome Centre for Human Neuroimaging (GB), Hebrew University of Jerusalem (IL), Centre Européen de Sociologie et de Science Politique (FR), Laboratoire Matière et Systèmes Complexes (FR), Max Planck Institute for Biology of Ageing (DE), Institut des Systèmes Complexes Paris Île-de-France (FR), University College London (GB)
Openalex Percentile: Top 62%
Mental Health via Writing
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