CD3+ immune cell endotypes are associated with PsA disease phenotype and response to advanced therapy: an integrated mass cytometry and proteomics cohort study
Heterogeneity in circulating immune cell profiles is associated with PsA clinical features and therapeutic response. The results underscore the potential of immune cell phenotyping to improve prognosis in PsA, which could inform personalised treatment strategies.
Authors
- Lihi Eder (ORCID: https://orcid.org/0000-0002-1473-1715)
- Liqun Diao (ORCID: https://orcid.org/0000-0003-2965-8220)
- Christopher T. Ritchlin (ORCID: https://orcid.org/0000-0002-2602-1219)
- Sydney Thib
- Stuti Dang (ORCID: https://orcid.org/0000-0002-7203-3229)
- Igor Jurišica (ORCID: https://orcid.org/0000-0002-2507-946X)
- Vincent Piguet (ORCID: https://orcid.org/0000-0001-6079-4517)
- Stéphane Caucheteux
- Xianwei Li (ORCID: https://orcid.org/0000-0002-6295-6089)
- Vinod Chandran
- Darshini Ganatra
Institutions
- Ontario Institute for Cancer Research (CA)
- University of Waterloo (CA)
- University of Toronto (CA)
- Women's College Hospital (CA)
- Krembil Foundation (CA)
- Krembil Research Institute
- University of Rochester (US)
Publication Details
- Journal
- Annals of the Rheumatic Diseases
- Published
- 2025-11-08
- DOI
- https://doi.org/10.1016/j.ard.2025.10.011
- Citations
- 1
- Primary Topic
- Immunodeficiency and Autoimmune Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.80
Funders
- National Psoriasis Foundation