Cellulosic Fabric Modification Using Pyrimidine Derivatives for Extending the Shelf Life of Raw Milk

Abstract In this study, two synthesized pyrimidine derivatives ( 2a and 2b ) were employed as modifiers for two textile substrates: 100% “Cotton” gauze (C) and 50/50% “Cotton/PET” (C/PET) to prepare filters for crude milk. The fabrics were modified using the pad/dry/curing technique. The effect of filtration on the shelf life of raw milk stored at temperatures of 20 and 5 °C was investigated using fabric filters. The chemical composition analysis of raw and filtered milk, including fat, protein, lactose, and solid non-fat content, was assessed. Similarly, a clot-on-boiling test, pH, and microbial content were investigated. The shelf life of the milk was extended from 8 to 20 h and from 4 to 6 days by filtration for samples stored at 20 and 5 °C, respectively, without any significant differences in chemical composition. Antibacterial activity of all treated fabrics and filtered milk was evaluated against pathogenic bacteria, Coliform, “ E. coli ”, and total molds, and the results showed high antimicrobial activity. The cytotoxicity of treated fabrics, as well as pyrimidine derivatives, was tested and displayed no cytotoxicity performance.