Rearrangement-driven divergent synthesis: a metal-free tandem annulation for CF <sub>3</sub> -functionalized 1-(aminomethyl)naphthalen-2-ols and 1-(2-naphthyl)azetidines

A novel metal- and base-free controllable tandem cyclization/rearrangement strategy for divergent synthesis of CF 3 -containing 1-(aminomethyl)naphthalen-2-ols and 1-(2-naphthyl)azetidines is established.

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Publication Details

Journal
Green Chemistry
Published
2025-01-01
DOI
https://doi.org/10.1039/d5gc05046d
Primary Topic
Synthesis and Catalytic Reactions
Type
article
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article

Rearrangement-driven divergent synthesis: a metal-free tandem annulation for CF 3 -functionalized 1-(aminomethyl)naphthalen-2-ols and 1-(2-naphthyl)azetidines

Hua Cao, Bin Wang, Zekun Li
Green Chemistry
Synthesis and Catalytic Reactions
article

Rearrangement-driven divergent synthesis: a metal-free tandem annulation for CF 3 -functionalized 1-(aminomethyl)naphthalen-2-ols and 1-(2-naphthyl)azetidines

Hua Cao, Bin Wang, Zekun Li
article en

Abstract

A novel metal- and base-free controllable tandem cyclization/rearrangement strategy for divergent synthesis of CF 3 -containing 1-(aminomethyl)naphthalen-2-ols and 1-(2-naphthyl)azetidines is established.

Green ChemistryVol. 27(47)
Guizhou University (CN), Guangdong Pharmaceutical University (CN)
Openalex Percentile: Top 75%
Synthesis and Catalytic Reactions
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