Prevalence of Inducible Clindamycin Resistant Staphylococcus Species in Clinical Isolates Recovered from Patients in Benin City, Nigeria

A total of 240 Staphylococci isolates were obtained from various clinical samples. These isolates were then identified using standard bacteriological techniques including colonial morphology, Gram staining, catalase and coagulase. The detection of lnducible clindamycin resistant (ICR) Staphylococcus species was done by D-Test method. Antimicrobial susceptibility test was performed using Kirby-Bauer diffusion method. The prevalence of ICR among Staphylococcus species obtained from this study was 22 (9.17%). Isolates that had inducible resistance to clindamycin was higher in methicillin resistant S. aureus isolates 16 (80.00%) than in methicillin sensitive S. aureus isolates 4 (20.00%). Resistance to cefotaxime recorded a significantly high prevalence in S. aureus 180 (96.78), CONS 54 (100.00%) and ICR 22 (100.00%) isolates. All isolates were more sensitive to imipenem/cilastin as compared to other antibiotics tested. The good oral absorption of clindamycin makes it an alternative option for use in treatment.