<scp>scRNA</scp> ‐Seq Reveals Sustained Pro‐Inflammation by Innate Immune Activation in In Utero <scp>HBV‐</scp> Exposed Neonates of High <scp>HBsAg</scp> Mothers
HBV exposure compromises adaptive immunity at birth; despite post-vaccination anti-HBs titres generation, there was a sustained pro-inflammatory state by the innate immune activation via metabolic alterations that persisted in neonates born to sAg<sup>Hi</sup> mothers.
Authors
- Prabhjyoti Pahwa
- Shiv Kumar Sarin (ORCID: https://orcid.org/0000-0002-0544-5610)
- Rajesh Pandey (ORCID: https://orcid.org/0000-0002-4404-8327)
- Nirupma Trehanpati (ORCID: https://orcid.org/0000-0002-6109-0033)
- Priyanka Mehta (ORCID: https://orcid.org/0000-0001-6298-4322)
- Partha Chattopadhyay (ORCID: https://orcid.org/0000-0002-5536-3162)
- Ashish Kumar Vyas (ORCID: https://orcid.org/0000-0001-6333-0195)
- Ravinder Singh (ORCID: https://orcid.org/0009-0001-6484-1365)
- Shakun Tyagi (ORCID: https://orcid.org/0000-0002-2462-4024)
- Sharda Patra
Institutions
- Lady Hardinge Medical College (IN)
- Lok Nayak Jai Prakash Narayan Hospital (IN)
- Institute of Liver and Biliary Sciences (IN)
- Amrita Vishwa Vidyapeetham (IN)
- Academy of Scientific and Innovative Research (IN)
Publication Details
- Journal
- Liver International
- Published
- 2025-11-07
- DOI
- https://doi.org/10.1111/liv.70405
- Primary Topic
- Hepatitis B Virus Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00