Mineralocorticoid Receptor in Glutamatergic Neurons Modulates Anxiety Exclusively in Male Mice Via Regulation of the Actin-Bundling Factor Fam107a
Together, our results underline the central role of MR as a potential target in understanding the intricate interplay between stress, resilience, and mental health.
Authors
- Lotte van Doeselaar (ORCID: https://orcid.org/0000-0003-1840-0574)
- Shiladitya Mitra (ORCID: https://orcid.org/0000-0002-0741-9424)
- Carlo De Donno (ORCID: https://orcid.org/0000-0002-9553-0121)
- Rosa-Eva Huettl (ORCID: https://orcid.org/0000-0001-8196-9865)
- Juan Pablo López (ORCID: https://orcid.org/0000-0002-5812-4220)
- Huanqing Yang (ORCID: https://orcid.org/0000-0002-8778-4789)
- Matthias Eder (ORCID: https://orcid.org/0000-0002-2579-2628)
- Mathias V. Schmidt (ORCID: https://orcid.org/0000-0002-3788-2268)
- Jan M. Deussing (ORCID: https://orcid.org/0000-0002-9329-5252)
- Alon Chen (ORCID: https://orcid.org/0000-0003-3625-8233)
- Lea M. Brix (ORCID: https://orcid.org/0000-0002-3655-4385)
- Margherita Springer (ORCID: https://orcid.org/0000-0002-2361-4940)
- Sowmya Narayan (ORCID: https://orcid.org/0000-0003-3675-1685)
- Joeri Bordes (ORCID: https://orcid.org/0000-0003-2909-2976)
- Marianne B. Müller (ORCID: https://orcid.org/0000-0002-0269-6131)
- Danusa Menegaz
Institutions
- Johannes Gutenberg University Mainz (DE)
- Karolinska Institutet (SE)
- Helmholtz Zentrum München (DE)
- Leibniz Institute for Resilience Research (DE)
- University Medical Center of the Johannes Gutenberg University Mainz (DE)
- Max Planck Institute of Psychiatry (DE)
- Weizmann Institute of Science (IL)
Publication Details
- Journal
- Biological Psychiatry Global Open Science
- Published
- 2025-11-08
- DOI
- https://doi.org/10.1016/j.bpsgos.2025.100651
- Primary Topic
- Stress Responses and Cortisol
- Type
- article
- Field-Weighted Citation Impact
- 0.00