Biopsy Morphometrics as Predictors of Treatment Response in Primary Nephrotic Syndrome
In patients with iNS, higher podocyte density and nonsclerotic glomerular density, and lower glomerulosclerosis and cortical fibrosis predicted CR. In patients with MN, lower glomerulosclerosis and higher nonsclerotic glomerular density predicted CR. Biopsy parameters may thus be useful for estimating proteinuria outcome.
Authors
- Jack F.M. Wetzels (ORCID: https://orcid.org/0000-0002-0650-6921)
- Bartholomeus T. van den Berge (ORCID: https://orcid.org/0000-0001-7246-2181)
- Bart Smeets (ORCID: https://orcid.org/0000-0002-8466-3367)
- Rutger Maas (ORCID: https://orcid.org/0000-0002-3006-4916)
- Coralien Vink
- Anne-Els van de Logt
- Jitske Jansen (ORCID: https://orcid.org/0000-0001-9920-0309)
- Quinty Leusink (ORCID: https://orcid.org/0009-0006-7885-4139)
- Sanne Kleuskens
- Sharon Bootsman
Institutions
- Radboud University Nijmegen (NL)
- Radboud University Medical Center (NL)
- Radboud Institute for Molecular Life Sciences (NL)
- RWTH Aachen University (DE)
Publication Details
- Journal
- Kidney Medicine
- Published
- 2025-11-08
- DOI
- https://doi.org/10.1016/j.xkme.2025.101181
- Citations
- 1
- Primary Topic
- Renal Diseases and Glomerulopathies
- Type
- article
- Field-Weighted Citation Impact
- 1.43