Dose-response assessment of neuroactive botanical extracts and their bioactive constituents using microelectrode array (MEA) recordings in rat primary cortical cultures
Botanical extracts and constituents evoke diverse activity phenotypes, highlighting the complexity of hazard characterization of botanicals.
Authors
- Constance A. Mitchell (ORCID: https://orcid.org/0000-0003-1052-7087)
- Remco H.S. Westerink (ORCID: https://orcid.org/0000-0003-4948-2007)
- Julie Krzykwa (ORCID: https://orcid.org/0000-0003-0929-6269)
- J. Pepijn Wopken
- Regina G.D.M. van Kleef
Institutions
- Utrecht University (NL)
- Health and Environmental Sciences Institute (US)
Publication Details
- Journal
- Pharmaceutical Biology
- Published
- 2025-11-07
- DOI
- https://doi.org/10.1080/13880209.2025.2583834
- Citations
- 1
- Primary Topic
- Phytochemistry and Biological Activities
- Type
- article
- Field-Weighted Citation Impact
- 1.75