Timing of vasopressin initiation influences renal outcomes in mixed cardiogenic-vasodilatory shock supported by VA-ECMO

Early vasopressin administration in VA-ECMO-supported mixed shock may reduce the incidence of acute kidney injury compared with no vasopressin use, without increasing adverse events. Prospective studies are warranted to confirm these findings and to determine the optimal timing of vasopressin therapy in this high-risk population.

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Publication Details

Journal
Anaesthesia Critical Care & Pain Medicine
Published
2025-11-08
DOI
https://doi.org/10.1016/j.accpm.2025.101670
Primary Topic
Mechanical Circulatory Support Devices
Type
article
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article

Timing of vasopressin initiation influences renal outcomes in mixed cardiogenic-vasodilatory shock supported by VA-ECMO

Maxime Nguyen, Vivien Berthoud, Bélaïd Bouhemad, Christophe Beyls et al.
Anaesthesia Critical Care & Pain Medicine
Mechanical Circulatory Support Devices
article

Timing of vasopressin initiation influences renal outcomes in mixed cardiogenic-vasodilatory shock supported by VA-ECMO

Maxime Nguyen, Vivien Berthoud, Bélaïd Bouhemad, Christophe Beyls, Guinot Pierre-Grégoire, Osama Abou-Ara
article en

Abstract

Early vasopressin administration in VA-ECMO-supported mixed shock may reduce the incidence of acute kidney injury compared with no vasopressin use, without increasing adverse events. Prospective studies are warranted to confirm these findings and to determine the optimal timing of vasopressin therapy in this high-risk population.

Anaesthesia Critical Care & Pain MedicineVol. 45(3)
Inserm (FR), Centre Hospitalier Universitaire Amiens-Picardie (FR), Maison des Sciences sociales et des Humanités de Dijon (FR)
Openalex Percentile: Top 68%
Mechanical Circulatory Support Devices
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