Cytokine Expression Profiling in Idiopathic Pulmonary Fibrosis: Insights From Integrative Proteomic Analysis
Using protein microarrays, we obtained comprehensive cytokine expression profiles in control and IPF lung tissues and conducted an integrated bioinformatics analysis of the proteomic data. Our findings may improve the comprehension of the role of cytokines in IPF and the underlying mechanisms. Moreover, they provide novel targets for developing safe and efficacious drugs for treating IPF.
Authors
- Xusheng Yang (ORCID: https://orcid.org/0000-0003-0769-778X)
- Yuan Chen (ORCID: https://orcid.org/0000-0002-8088-1471)
- Dong Wei (ORCID: https://orcid.org/0000-0002-4829-3258)
- Cheng Jiang (ORCID: https://orcid.org/0000-0002-8735-1254)
- Shugao Ye (ORCID: https://orcid.org/0009-0009-5547-2594)
- Chenyou Shen (ORCID: https://orcid.org/0000-0002-8220-0270)
- Jingyu Chen (ORCID: https://orcid.org/0000-0002-7854-3801)
- Wei Wang (ORCID: https://orcid.org/0000-0002-1614-0759)
- Gui‐Rong Li (ORCID: https://orcid.org/0000-0002-9437-2280)
- Jingjing Xu (ORCID: https://orcid.org/0000-0003-4501-1793)
- Yinghua Sheng (ORCID: https://orcid.org/0000-0003-4876-0546)
Institutions
- Wuxi People's Hospital (CN)
Publication Details
- Journal
- Canadian Respiratory Journal
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1155/carj/2272156
- Primary Topic
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China