The resistance trends in Mycobacterium kansasii pulmonary isolates and identification of risk factors for drug resistance in Taiwan
The study reveals increasing resistance to the first- and second-line agents in M. kansasii isolates across Taiwan. Resistance epidemiology differed between regions. Fibrocavitary lung lesion was significantly associated with drug resistance. These findings underscore the importance of region-specific surveillance to undergo individualized treatment strategies for M. kansasii pulmonary disease.
Authors
- Shang‐Yi Lin (ORCID: https://orcid.org/0000-0002-6336-4077)
- Sheng-Bin Fan
- Benjamin Sobkowiak (ORCID: https://orcid.org/0000-0002-1382-1137)
- Inn‐Wen Chong (ORCID: https://orcid.org/0000-0001-8328-8684)
- Hung‐Pin Tu (ORCID: https://orcid.org/0000-0003-1044-2673)
- Wei‐Chang Huang (ORCID: https://orcid.org/0000-0002-9733-5899)
- Meng‐Hsuan Cheng (ORCID: https://orcid.org/0000-0001-8135-7877)
- Hung‐Ling Huang (ORCID: https://orcid.org/0000-0001-8809-0546)
- Po-Liang Lu
- Yi‐Wen Huang (ORCID: https://orcid.org/0000-0002-5196-7030)
Institutions
- Ministry of Health and Welfare (KR)
- Kaohsiung Medical University (TW)
- National Chung Hsing University (TW)
- Taichung Veterans General Hospital (TW)
- Chung Shan Medical University Hospital (TW)
- Pingtung Hospital (TW)
- Institute of Infection and Immunity (CA)
- University College London (GB)
- Chung Shan Medical University (TW)
Publication Details
- Journal
- Journal of Global Antimicrobial Resistance
- Published
- 2025-11-08
- DOI
- https://doi.org/10.1016/j.jgar.2025.11.001
- Primary Topic
- Mycobacterium research and diagnosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00