An Update of Clinically Significant Grapefruit Juice-Drug Interactions

Grapefruit juice is typically consumed in the morning while many patients take their medications. Therefore, there is a concern among healthcare professionals that this may result in clinically significant drug interactions. This review examines the current understanding of drug–grapefruit juice interactions, along with examples of specific medications affected by the ingestion of grapefruit juice.

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Publication Details

Journal
Nutrition Today
Published
2025-11-06
DOI
https://doi.org/10.1097/nt.0000000000000784
Primary Topic
Pharmacology and Obesity Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

An Update of Clinically Significant Grapefruit Juice-Drug Interactions

Suzanne Dinsmore, R. Rebecca Couris, Mary-Kathleen Grams
Nutrition Today
Pharmacology and Obesity Treatment
article

An Update of Clinically Significant Grapefruit Juice-Drug Interactions

Suzanne Dinsmore, R. Rebecca Couris, Mary-Kathleen Grams
article en

Abstract

Grapefruit juice is typically consumed in the morning while many patients take their medications. Therefore, there is a concern among healthcare professionals that this may result in clinically significant drug interactions. This review examines the current understanding of drug–grapefruit juice interactions, along with examples of specific medications affected by the ingestion of grapefruit juice.

Nutrition TodayVol. 61(1)
Massachusetts College of Pharmacy and Health Sciences (US), Grace (United States) (US), DOT (Germany) (DE)
Openalex Percentile: Top 63%
Pharmacology and Obesity Treatment
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