Combining genetic and behavioral predictors of 11-year language outcome
Polygenic scores derived for toddlerhood vocabulary did not meaningfully improve predictive accuracy of individuals' language outcome when added to the phenotypic predictor set. Presently, parent-reported measures or clinician observation appear best for predicting language outcome at this age.
Authors
- Daisy A. Shepherd (ORCID: https://orcid.org/0000-0001-8540-0473)
- Ellen Verhoef (ORCID: https://orcid.org/0000-0002-8315-1095)
- Sheena Reilly (ORCID: https://orcid.org/0000-0001-6506-4767)
- Jing Wang (ORCID: https://orcid.org/0000-0001-5701-476X)
- Melissa A Wake (ORCID: https://orcid.org/0000-0001-7501-9257)
- Angela Tamsin Morgan (ORCID: https://orcid.org/0000-0003-1147-7405)
- Beaté St Pourcain (ORCID: https://orcid.org/0000-0002-4680-3517)
- Katherine Lange (ORCID: https://orcid.org/0000-0002-8175-6285)
- Edith L. Bavin (ORCID: https://orcid.org/0000-0002-7580-149X)
- Loretta Gasparini (ORCID: https://orcid.org/0000-0002-1561-5572)
Institutions
- Royal Children's Hospital (AU)
- Radboud University Nijmegen (NL)
- Max Planck Institute for Psycholinguistics (NL)
Publication Details
- Journal
- Psychiatry Research
- Published
- 2025-11-08
- DOI
- https://doi.org/10.1016/j.psychres.2025.116826
- Primary Topic
- Language Development and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Children’s Hospital of Wisconsin Research Institute
- Children's Hospital Foundation
- Murdoch Children's Research Institute
- Royal Children's Hospital Foundation
- Australian Government
- Department of Social Services, Australian Government
- National Heart Foundation of Australia
- La Trobe University
- University of Melbourne
- Max-Planck-Gesellschaft
- State Government of Victoria
- Medical Research Council
- National Health and Medical Research Council