Evaluation of an enzymatic one-step assay for Beta-Hydroxybutyrate blood testing on clinical chemistry platforms using HILIC-MS/MS as a non-enzymatic reference method
The DiaSys BHB 21 FS assay combines robust analytical performance and high concordance with both enzymatic and mass spectrometric methods. These features support its use as a reliable one-step assay for routine clinical assessment of ketosis and ketoacidosis.
Authors
- Max K. Steinbach
- Holger N. Müller
- Tobias Frömel (ORCID: https://orcid.org/0000-0003-4812-0127)
- Allen Lein
- Kai Prager
- Matthias Grimmler (ORCID: https://orcid.org/0000-0003-2860-3391)
- Christoph Peter (ORCID: https://orcid.org/0000-0002-0048-2279)
- Yanik Reichard
- Konstantin Eulberg
Institutions
- Hochschule Fresenius (DE)
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- Clinica Chimica Acta
- Published
- 2025-11-08
- DOI
- https://doi.org/10.1016/j.cca.2025.120703
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00