Single-cell profiling unveils the immuno-favorable tumor microenvironment remodeling after successful neoadjuvant therapy for advanced gallbladder cancer
This study suggested the potential efficacy of NAT in advanced GBC and revealed alterations in the TME following treatment. The findings provided insights into the mechanisms underlying NAT responses and offered valuable directions for optimizing therapeutic strategies in GBC.
Authors
- Wenting Dai (ORCID: https://orcid.org/0000-0002-8851-5556)
- Ziyi Yang (ORCID: https://orcid.org/0000-0001-5883-9552)
- Chuanxin Huang (ORCID: https://orcid.org/0000-0003-2667-9587)
- Yue Yang (ORCID: https://orcid.org/0000-0003-2179-5562)
- Qiu‐Yi Tang (ORCID: https://orcid.org/0000-0001-9459-4433)
- Yi‐Jian Zhang (ORCID: https://orcid.org/0000-0002-3810-6711)
- Lin Jiang (ORCID: https://orcid.org/0000-0002-0947-1760)
- Yangyang Zhai
- Cheng Zhao (ORCID: https://orcid.org/0000-0001-8385-6987)
- Yu Zhao (ORCID: https://orcid.org/0000-0001-9025-2014)
- Tianyu Zhang (ORCID: https://orcid.org/0000-0001-5647-6014)
- Xiaoling Song (ORCID: https://orcid.org/0000-0002-0321-5379)
- Yu Zhang (ORCID: https://orcid.org/0000-0002-3463-9350)
- Zi-you Wu (ORCID: https://orcid.org/0000-0002-6780-9870)
- Wei Gong (ORCID: https://orcid.org/0000-0002-9949-6207)
- Xiangsong Wu
- Hua-Kai Wang
- Yidi Zhu
Institutions
- Army Medical University (CN)
- Shanghai Jiao Tong University (CN)
- XinHua Hospital (CN)
- Southwest Hospital (CN)
- WengFu Group (China) (CN)
Publication Details
- Journal
- International Journal of Surgery
- Published
- 2025-11-06
- DOI
- https://doi.org/10.1097/js9.0000000000003883
- Primary Topic
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00