Role of Cell Culture Scaffold Stiffness on Sonoporation Efficiency
Our findings highlight the critical role of mechanical scaffold properties in determining sonoporation outcomes, where softer scaffolds result in reduced membrane disruption and altered pore formation dynamics despite unchanged bubble oscillation behavior.
Authors
- Tim Segers (ORCID: https://orcid.org/0000-0001-5428-1547)
- Michel Versluis (ORCID: https://orcid.org/0000-0002-2296-1860)
- Alfred C. H. Yu (ORCID: https://orcid.org/0000-0002-8604-0219)
- R.B. Bryan Klassen
- Martin R. P. van den Broek (ORCID: https://orcid.org/0009-0007-6424-9170)
Institutions
- Max Planck University of Twente Center for Complex Fluid Dynamics (NL)
- Research Institute for Aging (CA)
Publication Details
- Journal
- Ultrasound in Medicine & Biology
- Published
- 2025-11-07
- DOI
- https://doi.org/10.1016/j.ultrasmedbio.2025.09.018
- Primary Topic
- Lipid Membrane Structure and Behavior
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- European Commission