Pricing Trends and Overlapping Indications of Checkpoint Inhibitors for Cancer Treatment

Prices of checkpoint inhibitors have decreased only slightly since introduction. This may be partially explained by lack of overlapping indications, which hinders direct competition among within-class drugs. Expanding drug price negotiations or incentivizing comparative effectiveness research may help to promote competition and address high prices.

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Publication Details

Journal
JCO Oncology Practice
Published
2025-11-07
DOI
https://doi.org/10.1200/op-25-00099
Primary Topic
Economic and Financial Impacts of Cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Pricing Trends and Overlapping Indications of Checkpoint Inhibitors for Cancer Treatment

Aaron Philip Mitchell, Jeddeo M. Paul, Aaron Seth Kesselheim, Benjamin N. Rome
JCO Oncology Practice
Economic and Financial Impacts of Cancer
article

Pricing Trends and Overlapping Indications of Checkpoint Inhibitors for Cancer Treatment

Aaron Philip Mitchell, Jeddeo M. Paul, Aaron Seth Kesselheim, Benjamin N. Rome
article en

Abstract

Prices of checkpoint inhibitors have decreased only slightly since introduction. This may be partially explained by lack of overlapping indications, which hinders direct competition among within-class drugs. Expanding drug price negotiations or incentivizing comparative effectiveness research may help to promote competition and address high prices.

JCO Oncology Practice
Brigham and Women's Hospital (US), Memorial Sloan Kettering Cancer Center (US), Harvard University (US), Stanford Medicine (US), Stanford University (US)
Openalex Percentile: Top 58%
Economic and Financial Impacts of Cancer
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Pricing Trends and Overlapping Indications of Checkpoint Inhibitors for Cancer Treatment — Aaron Philip Mitchell, Jeddeo M. Paul, et al. · JCO Oncology Practice (2025) | TGRS Research Map | TGRS