missForestPredict—Missing data imputation for prediction settings

Prediction models are used to predict an outcome based on input variables. Missing data in input variables often occur at model development and at prediction time. The missForestPredict R package proposes an adaptation of the missForest imputation algorithm that is fast, user-friendly and tailored for prediction settings. The algorithm iteratively imputes variables using random forests until a convergence criterion, unified for continuous and categorical variables, is met. The imputation models are saved for each variable and iteration and can be applied later to new observations at prediction time. The missForestPredict package offers extended error monitoring, control over variables used in the imputation and custom initialization. This allows users to tailor the imputation to their specific needs. The missForestPredict algorithm is compared to mean/mode imputation, linear regression imputation, mice, k-nearest neighbours, bagging, miceRanger and IterativeImputer on eight simulated datasets with simulated missingness (48 scenarios) and eight large public datasets using different prediction models. missForestPredict provides competitive results in prediction settings within short computation times.

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Publication Details

Journal
PLoS ONE
Published
2025-11-07
DOI
https://doi.org/10.1371/journal.pone.0334125
Primary Topic
Statistical Methods and Bayesian Inference
Type
article
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article

missForestPredict—Missing data imputation for prediction settings

Laure Wynants, Ben Van Calster, Elena Albu, Shan Gao
PLoS ONE
Statistical Methods and Bayesian Inference
article

missForestPredict—Missing data imputation for prediction settings

Laure Wynants, Ben Van Calster, Elena Albu, Shan Gao
article en

Abstract

Prediction models are used to predict an outcome based on input variables. Missing data in input variables often occur at model development and at prediction time. The missForestPredict R package proposes an adaptation of the missForest imputation algorithm that is fast, user-friendly and tailored for prediction settings. The algorithm iteratively imputes variables using random forests until a convergence criterion, unified for continuous and categorical variables, is met. The imputation models are saved for each variable and iteration and can be applied later to new observations at prediction time. The missForestPredict package offers extended error monitoring, control over variables used in the imputation and custom initialization. This allows users to tailor the imputation to their specific needs. The missForestPredict algorithm is compared to mean/mode imputation, linear regression imputation, mice, k-nearest neighbours, bagging, miceRanger and IterativeImputer on eight simulated datasets with simulated missingness (48 scenarios) and eight large public datasets using different prediction models. missForestPredict provides competitive results in prediction settings within short computation times.

PLoS ONEVol. 20(11)
Maastricht University (NL), KU Leuven (BE)
Openalex Percentile: Top 69%
Statistical Methods and Bayesian Inference
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missForestPredict—Missing data imputation for prediction settings — Laure Wynants, Ben Van Calster, et al. · PLoS ONE (2025) | TGRS Research Map | TGRS