A systematic comparison of patient information leaflets from local and multinational pharmaceutical companies: Assessing content quality and completeness
Multinational and local PILs, both performed well in providing basic information on active ingredients, brand names, contraindications, pregnancy, and lactation details. However, disparities among various aspects including inactive ingredient, specific dosing, dose adjusments and drug interactions between PILS of multinational and local pharmaceutical companies in Pakistan highlights the necessity for regulatory measures and industry initiatives to standardize PIL content. For ensuring patient safety and enhancing the quality of medication use it is essential to improve the comprehensiveness and clarity of PILs.
Authors
- Omar Awad Alsaidan (ORCID: https://orcid.org/0000-0002-2848-2932)
- Azfar Athar Ishaqui (ORCID: https://orcid.org/0000-0003-0688-2625)
- Tauqeer Hussain Mallhi (ORCID: https://orcid.org/0000-0001-9957-5362)
- Sami I. Alzarea (ORCID: https://orcid.org/0000-0003-4007-4023)
- Abdullah Salah Alanazi (ORCID: https://orcid.org/0000-0002-8120-4018)
- Muhammad Zeeshan (ORCID: https://orcid.org/0000-0001-8873-9632)
- Yusra Habib Khan (ORCID: https://orcid.org/0000-0002-9479-6147)
- Muhammad Salman (ORCID: https://orcid.org/0000-0001-8025-4622)
- Javeria Farooq (ORCID: https://orcid.org/0000-0001-9645-0417)
- Abdulaziz Ibrahim Alzarea (ORCID: https://orcid.org/0000-0003-0604-6299)
- Hassan H. Alhassan (ORCID: https://orcid.org/0000-0002-7174-9831)
- Aseel Awad Alsaidan (ORCID: https://orcid.org/0000-0003-0220-6160)
Institutions
- St. Gregory's University (US)
- Lahore College for Women University (PK)
- Iqra University (PK)
- University of Karachi (PK)
- Jouf University (SA)
- Taylor's University (MY)
- King Khalid University (SA)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-11-07
- DOI
- https://doi.org/10.1371/journal.pone.0335149
- Primary Topic
- Pharmaceutical Quality and Counterfeiting
- Type
- article
- Field-Weighted Citation Impact
- 0.00