Identifying autophagy-related biomarkers in the treatment of renal interstitial fibrosis with Shen Fukang through network pharmacology

This study successfully identified FOS and IFNG as 2 key biomarkers related to autophagy in the treatment of RIF by SFK. Through a series of analyses, including GeneMANIA analysis, enrichment analysis, regulatory network construction, and molecular docking, the potential molecular mechanisms associated with these biomarkers were comprehensively explored.

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Publication Details

Journal
Medicine
Published
2025-11-07
DOI
https://doi.org/10.1097/md.0000000000045536
Primary Topic
Chronic Kidney Disease and Diabetes
Type
article
Field-Weighted Citation Impact
0.00
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article

Identifying autophagy-related biomarkers in the treatment of renal interstitial fibrosis with Shen Fukang through network pharmacology

Simiao Liu, Yaqi Gong, Zihao Zhang, Jingsong Liu
Medicine
Chronic Kidney Disease and Diabetes
article

Identifying autophagy-related biomarkers in the treatment of renal interstitial fibrosis with Shen Fukang through network pharmacology

Simiao Liu, Yaqi Gong, Zihao Zhang, Jingsong Liu
article en

Abstract

This study successfully identified FOS and IFNG as 2 key biomarkers related to autophagy in the treatment of RIF by SFK. Through a series of analyses, including GeneMANIA analysis, enrichment analysis, regulatory network construction, and molecular docking, the potential molecular mechanisms associated with these biomarkers were comprehensively explored.

MedicineVol. 104(45)
Hunan University of Traditional Chinese Medicine (CN), Hunan Academy of Traditional Chinese Medicine (CN)
Openalex Percentile: Top 61%
Chronic Kidney Disease and Diabetes
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