Novel variants related to extreme elevation of serum IgE in Vietnamese patients with primary immunodeficiency: Case report
We report novel variants associated with genetic defects that increase IgE found in PID patients. These results emphasize the need for accurate diagnosis and appropriate intervention to improve outcomes and quality of care for individuals with high IgE levels and related immune disorders.
Authors
- Ngo Diem Ngoc
- Nguyen Minh Thu (ORCID: https://orcid.org/0000-0001-9620-809X)
- Nguyen Thi Kim Lien (ORCID: https://orcid.org/0000-0002-7562-0381)
- Nguyen Van Tung (ORCID: https://orcid.org/0000-0003-4624-5567)
- Trần Minh Điền (ORCID: https://orcid.org/0000-0003-4012-764X)
- Nguyễn Huy Hoàng (ORCID: https://orcid.org/0000-0002-6284-5813)
- Nguyen Thi Thanh Ngan
- Thi Ngoc Phuong Nguyen (ORCID: https://orcid.org/0000-0002-3615-0698)
- Lê Thị Minh Hương (ORCID: https://orcid.org/0000-0003-1655-799X)
- Nguyễn Thị Vân Anh (ORCID: https://orcid.org/0009-0002-5810-9765)
- Nguyễn Thanh Hiển (ORCID: https://orcid.org/0009-0004-3844-6937)
Institutions
- Phenikaa University (VN)
- Vietnam National Children's Hospital (VN)
- Ministry of Health (VN)
- S.P.E.C.I.E.S. (US)
- Vietnam Academy of Science and Technology (VN)
Publication Details
- Journal
- Medicine
- Published
- 2025-11-07
- DOI
- https://doi.org/10.1097/md.0000000000045565
- Primary Topic
- Immunodeficiency and Autoimmune Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00