Regulation and mechanism of chloride channels in proliferative vitreoretinopathy
By reducing the opening of chloride channels within RPE cells via drugs, PVR formation can be suppressed, which is sufficient to counteract retinal degeneration. Chloride channels may have crucial effects on RPE cell proliferation and migration. The therapeutic strategy of blocking chloride channels may be beneficial for PVR.
Authors
- Weibo Wen (ORCID: https://orcid.org/0000-0003-3404-2738)
- Xiangdan Li (ORCID: https://orcid.org/0000-0002-3002-5482)
- Lixia Sun (ORCID: https://orcid.org/0000-0003-0856-4495)
- Meiling Jiang (ORCID: https://orcid.org/0000-0001-9985-3510)
- Dongyuan Xu (ORCID: https://orcid.org/0000-0002-3055-6320)
- Yingfeng Liu (ORCID: https://orcid.org/0000-0003-2225-117X)
Institutions
- Yanbian University (CN)
- Yanbian University Hospital (CN)
Publication Details
- Journal
- Medicine
- Published
- 2025-11-07
- DOI
- https://doi.org/10.1097/md.0000000000045721
- Primary Topic
- Retinal Development and Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00