QbD-guided development of a simvastatin-loaded transethosomal gel for enhanced transdermal delivery: optimization, characterization, and <i>in vivo</i> antihyperlipidemic evaluation

The simvastatin-loaded transethosomal gel demonstrated superior dermal delivery, efficacy, and safety, supporting its potential as a nanoenabled transdermal alternative for hyperlipidemia management.

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Publication Details

Journal
Drug Development and Industrial Pharmacy
Published
2025-11-07
DOI
https://doi.org/10.1080/03639045.2025.2586232
Primary Topic
Advancements in Transdermal Drug Delivery
Type
article
Field-Weighted Citation Impact
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article

QbD-guided development of a simvastatin-loaded transethosomal gel for enhanced transdermal delivery: optimization, characterization, and in vivo antihyperlipidemic evaluation

Panchaxari M. Dandagi, Umashri A. Kokatanur, S. S. Patil
Drug Development and Industrial Pharmacy
Advancements in Transdermal Drug Delivery
article

QbD-guided development of a simvastatin-loaded transethosomal gel for enhanced transdermal delivery: optimization, characterization, and in vivo antihyperlipidemic evaluation

Panchaxari M. Dandagi, Umashri A. Kokatanur, S. S. Patil
article en

Abstract

The simvastatin-loaded transethosomal gel demonstrated superior dermal delivery, efficacy, and safety, supporting its potential as a nanoenabled transdermal alternative for hyperlipidemia management.

Drug Development and Industrial PharmacyVol. 52(1)
KLE Academy of Higher Education and Research (IN)
Openalex Percentile: Top 74%
Advancements in Transdermal Drug Delivery
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