Prospective, randomized, controlled trial comparing PROpofol versus KetaMINE in rapid sequence intubation in critically ill patients (PROMINE): protocol paper and statistical analysis plan
The PROMINE study will provide valuable evidence to guide the selection of hypnotic agents for rapid sequence intubation in critically ill patients. It will contribute to a better understanding of the hemodynamic effects associated with propofol and ketamine in this context, potentially informing clinical practice.
Authors
- Fernando José da Silva Ramos (ORCID: https://orcid.org/0000-0002-5277-4759)
- Lucas Petri Damiani (ORCID: https://orcid.org/0000-0002-5836-3379)
- Flávio Geraldo Rezende de Freitas (ORCID: https://orcid.org/0000-0002-7144-6494)
- Fernández Serra (ORCID: https://orcid.org/0009-0005-9452-5821)
- Raysa Cristina Schmidt (ORCID: https://orcid.org/0000-0002-9777-113X)
- Flávia Ribeiro Machado (ORCID: https://orcid.org/0000-0002-2356-4867)
- Fernando Godinho Zampieri (ORCID: https://orcid.org/0000-0001-9315-6386)
Institutions
- Hospital do Coração (BR)
- Hospital São Paulo (BR)
- Universidade Federal de São Paulo (BR)
Publication Details
- Journal
- Critical Care Science
- Published
- 2025-01-01
- DOI
- https://doi.org/10.62675/2965-2774.20250133
- Citations
- 1
- Primary Topic
- Anesthesia and Sedative Agents
- Type
- article
- Field-Weighted Citation Impact
- 2.19
Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico