Temperature-jump QCL spectroscopy of peptide dynamics: expanding spectral accessibility by dual-combs
Combining infrared dual-comb spectroscopy with laser-induced nanosecond temperature-jumps enables fast tracking of peptide folding dynamics. Compared to single-wavenumber quantum cascade lasers, this method provides broader spectral information. Using a model peptide system, the study opens new perspectives for applying time-resolved IR spectroscopy to explore mechanistic details in biomolecular dynamics.
Authors
- Paul Stritt (ORCID: https://orcid.org/0000-0003-3139-560X)
- Raphael Horvath (ORCID: https://orcid.org/0000-0002-2695-4895)
- Manuel Oestringer (ORCID: https://orcid.org/0000-0002-3929-9287)
- Andreas Hugi (ORCID: https://orcid.org/0009-0007-7317-5302)
- Karin Hauser (ORCID: https://orcid.org/0000-0003-0546-9038)
- Lorenz Mattes (ORCID: https://orcid.org/0009-0009-1975-1449)
Institutions
- University of Konstanz (DE)
- Sensirion (Switzerland) (CH)
Publication Details
- Journal
- Chemical Communications
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1039/d5cc04629g
- Primary Topic
- Advanced Fiber Laser Technologies
- Type
- article
- Field-Weighted Citation Impact
- 0.00