Approaches to Mechanical Ventilation in Patients With and Without Acute Brain Injury: A Registry-Based Cohort Study
Both ABI and non-ABI patients received comparable V t that trended downwards over time. Pa co2 and Pa o2 remained largely within guideline-recommended ranges. However, PEEP was significantly lower in ABI patients, including among those with hypoxemic respiratory failure, highlighting potential opportunities to improve PEEP application in relevant subsets.
Authors
- Irene Telías (ORCID: https://orcid.org/0000-0002-6520-7040)
- Jeffrey M. Singh (ORCID: https://orcid.org/0000-0003-3499-574X)
- Federico Angriman (ORCID: https://orcid.org/0000-0003-0971-386X)
- Thiago Bassi (ORCID: https://orcid.org/0000-0001-5570-5057)
- Victoria McCredie (ORCID: https://orcid.org/0000-0002-1590-2846)
- Shaurya Taran (ORCID: https://orcid.org/0000-0001-7639-0365)
- You Lü (ORCID: https://orcid.org/0000-0002-7524-4179)
- Eddy Fan (ORCID: https://orcid.org/0000-0002-1210-9914)
Institutions
- Sunnybrook Health Science Centre (CA)
- University Health Network (CA)
- University of Toronto (CA)
- Toronto General Hospital (CA)
- Health Sciences Centre (CA)
- Lungpacer Medical (Canada) (CA)
- Toronto General Hospital Research Institute
Publication Details
- Journal
- Critical Care Medicine
- Published
- 2025-11-07
- DOI
- https://doi.org/10.1097/ccm.0000000000006931
- Citations
- 1
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.52