Extending regular oral hygiene reduces the incidence of upper respiratory symptoms
In this randomized controlled clinical study, the effectiveness of two different modes of extending oral hygiene - either gargling or using an oral spray - on the self-reported incidence of upper respiratory symptoms were evaluated, to help with the prevention of respiratory symptoms. The study was conducted in Porto Alegre, Brazil. A total of 205 individuals were enrolled and assigned to one of three groups: Control Group: brushed twice daily for two minutes with a commercially available fluoride toothpaste; Gargling Group: brushed twice daily for two minutes with a commercially available fluoride toothpaste and then gargled with a mouthwash containing 0.075% CPC (cetylpiridinium chloride); and Oral Spray Group: brushed twice daily for two minutes with a commercially available fluoride toothpaste and instructed to use an oral spray containing 0.075% CPC (3 pumps of spray applied directly into their mouth) twice daily. All subjects were asked to complete the WURSS-21 Daily Symptom Report via a diary for the 3 months duration of the study. Based on analysis of the diaries, the use of regular oral hygiene with brushing, in addition to a type that extended to the entire oral cavity, reduced the incidence and severity of upper respiratory symptoms throughout the duration of the study. Data were statistically analyzed using ANOVA (α = 0.05). Individuals using either mouthwash or spray reported approximately 20% fewer days with respiratory symptoms compared with the control group. Regular oral hygiene that extended to the whole oral cavity with either a mouthwash or an oral spray may help to reduce the incidence of upper respiratory symptoms.
Authors
- Zilson Malheiros (ORCID: https://orcid.org/0000-0003-0999-7217)
- Rodrigo de Oliveira Caetano (ORCID: https://orcid.org/0000-0001-6486-9344)
- Lorena Lírio Sossai (ORCID: https://orcid.org/0000-0003-3620-8076)
- Isadora dos Santos Rotta (ORCID: https://orcid.org/0000-0003-2373-6160)
- Lyndsay M. Schaeffer (ORCID: https://orcid.org/0009-0002-6038-0634)
- Cassiano Kuchenbecker Rõsing (ORCID: https://orcid.org/0000-0002-8499-5759)
- Carlos Benítez (ORCID: https://orcid.org/0000-0002-8512-6176)
- Bernal Stewart (ORCID: https://orcid.org/0000-0002-3054-4098)
- Juliano Cavagni (ORCID: https://orcid.org/0000-0003-0062-6604)
- Gabrielle PEDRONI (ORCID: https://orcid.org/0000-0001-7640-2901)
- Stephanie Friedrich (ORCID: https://orcid.org/0000-0003-2270-8934)
Institutions
- Universidade Federal do Rio Grande do Sul (BR)
- Colgate-Palmolive (Switzerland) (CH)
- Colgate-Palmolive (United States) (US)
Publication Details
- Journal
- Brazilian Oral Research
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1590/1807-3107bor-2025.vol39.118
- Citations
- 1
- Primary Topic
- Dental Research and COVID-19
- Type
- article
- Field-Weighted Citation Impact
- 2.82