Extending regular oral hygiene reduces the incidence of upper respiratory symptoms

In this randomized controlled clinical study, the effectiveness of two different modes of extending oral hygiene - either gargling or using an oral spray - on the self-reported incidence of upper respiratory symptoms were evaluated, to help with the prevention of respiratory symptoms. The study was conducted in Porto Alegre, Brazil. A total of 205 individuals were enrolled and assigned to one of three groups: Control Group: brushed twice daily for two minutes with a commercially available fluoride toothpaste; Gargling Group: brushed twice daily for two minutes with a commercially available fluoride toothpaste and then gargled with a mouthwash containing 0.075% CPC (cetylpiridinium chloride); and Oral Spray Group: brushed twice daily for two minutes with a commercially available fluoride toothpaste and instructed to use an oral spray containing 0.075% CPC (3 pumps of spray applied directly into their mouth) twice daily. All subjects were asked to complete the WURSS-21 Daily Symptom Report via a diary for the 3 months duration of the study. Based on analysis of the diaries, the use of regular oral hygiene with brushing, in addition to a type that extended to the entire oral cavity, reduced the incidence and severity of upper respiratory symptoms throughout the duration of the study. Data were statistically analyzed using ANOVA (α = 0.05). Individuals using either mouthwash or spray reported approximately 20% fewer days with respiratory symptoms compared with the control group. Regular oral hygiene that extended to the whole oral cavity with either a mouthwash or an oral spray may help to reduce the incidence of upper respiratory symptoms.

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Publication Details

Journal
Brazilian Oral Research
Published
2025-01-01
DOI
https://doi.org/10.1590/1807-3107bor-2025.vol39.118
Citations
1
Primary Topic
Dental Research and COVID-19
Type
article
Field-Weighted Citation Impact
2.82
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article

Extending regular oral hygiene reduces the incidence of upper respiratory symptoms

Zilson Malheiros, Rodrigo de Oliveira Caetano, Lorena Lírio Sossai, Isadora dos Santos Rotta et al.
1 citations
Brazilian Oral Research
Dental Research and COVID-19
2.82
article

Extending regular oral hygiene reduces the incidence of upper respiratory symptoms

Zilson Malheiros, Rodrigo de Oliveira Caetano, Lorena Lírio Sossai, Isadora dos Santos Rotta, Lyndsay M. Schaeffer, Cassiano Kuchenbecker Rõsing, Carlos Benítez, Bernal Stewart, Juliano Cavagni, Gabrielle PEDRONI, Stephanie Friedrich
article en
1 citations

Abstract

In this randomized controlled clinical study, the effectiveness of two different modes of extending oral hygiene - either gargling or using an oral spray - on the self-reported incidence of upper respiratory symptoms were evaluated, to help with the prevention of respiratory symptoms. The study was conducted in Porto Alegre, Brazil. A total of 205 individuals were enrolled and assigned to one of three groups: Control Group: brushed twice daily for two minutes with a commercially available fluoride toothpaste; Gargling Group: brushed twice daily for two minutes with a commercially available fluoride toothpaste and then gargled with a mouthwash containing 0.075% CPC (cetylpiridinium chloride); and Oral Spray Group: brushed twice daily for two minutes with a commercially available fluoride toothpaste and instructed to use an oral spray containing 0.075% CPC (3 pumps of spray applied directly into their mouth) twice daily. All subjects were asked to complete the WURSS-21 Daily Symptom Report via a diary for the 3 months duration of the study. Based on analysis of the diaries, the use of regular oral hygiene with brushing, in addition to a type that extended to the entire oral cavity, reduced the incidence and severity of upper respiratory symptoms throughout the duration of the study. Data were statistically analyzed using ANOVA (α = 0.05). Individuals using either mouthwash or spray reported approximately 20% fewer days with respiratory symptoms compared with the control group. Regular oral hygiene that extended to the whole oral cavity with either a mouthwash or an oral spray may help to reduce the incidence of upper respiratory symptoms.

Brazilian Oral ResearchVol. 39
Universidade Federal do Rio Grande do Sul (BR), Colgate-Palmolive (Switzerland) (CH), Colgate-Palmolive (United States) (US)
Openalex Percentile: Top 8%
Dental Research and COVID-19
2.82
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