KRAS G12A Identifies a High-Risk Subset in Resected Stage II–III Colorectal Cancer
Across two cohorts, KRAS G12A identified a small but clinically meaningful high-risk subset of stage II-III CRC characterized by early recurrence and inferior survival. Recognition of this variant may inform postoperative risk stratification in the adjuvant setting.
Authors
- Kosaku Mimura (ORCID: https://orcid.org/0000-0003-2565-154X)
- Zenichiro Saze (ORCID: https://orcid.org/0000-0003-2188-0951)
- Masanori Katagata
- Shun Chida
- Atsuko Fujii (ORCID: https://orcid.org/0009-0000-1145-2289)
- Tomoyuki Momma (ORCID: https://orcid.org/0000-0002-2911-5800)
- Daisuke Ujiie
- Hirokazu Okayama (ORCID: https://orcid.org/0000-0003-0966-4746)
- Daiki Yamaguchi (ORCID: https://orcid.org/0000-0001-7226-7482)
- Shotaro Nakajima (ORCID: https://orcid.org/0000-0002-9339-3792)
- Motonobu Saito (ORCID: https://orcid.org/0000-0001-5072-3520)
- Sohei Hayashishita
- Wataru Sakamoto (ORCID: https://orcid.org/0000-0001-7045-5834)
- Takuro Matsumoto (ORCID: https://orcid.org/0000-0001-5589-8573)
- Koji Kono (ORCID: https://orcid.org/0000-0003-0106-2767)
Institutions
- Fukushima Medical University (JP)
- Fukushima Medical University Hospital (JP)
Publication Details
- Journal
- Cancers
- Published
- 2025-11-07
- DOI
- https://doi.org/10.3390/cancers17223599
- Primary Topic
- Colorectal Cancer Treatments and Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00