The role of the clinical laboratory in the study of mesalazine-induced nephrolithiasis and crystalluria

The scarce literature available on the association between the use of mesalazine and increased risk of lithiasis fails to provide frequency data. Only a previous case on mesalazine crystalluria had been reported in the literature so far, probably due to the difficulty detecting this complication. This case series emphasizes the role of urine sediment analysis in identifying crystalluria and preventing major complications during the follow-up of patients receiving mesalazine therapy.