A diagnosis confused with hereditary angioedema: nephrotic syndrome

Hereditary angioedema (HAE) is a rare, autosomal dominant disease that primarily affects the skin, upper respiratory tract, and gastrointestinal system.Nephrotic syndrome (NS) is defined by the presence of severe proteinuria, low serum albumin levels, and generalized edema.Periorbital edema seen in NS can be confused with allergic edema or HAE.Accurate differential diagnosis is essential for appropriate treatment.This report presents a case of NS initially misdiagnosed as HAE.