Multi-omics analyses identify mannose phosphate isomerase-centered hypoxia-induced angiogenesis signature in colorectal cancer
This study depicts the transcriptional landscape linking hypoxia and angiogenesis in CRC, and identifies MPI as a novel regulator of this process.
Authors
- Junhong Han (ORCID: https://orcid.org/0000-0002-3371-8698)
- Sicheng Liu (ORCID: https://orcid.org/0000-0001-7332-8267)
- Linda Wen (ORCID: https://orcid.org/0009-0004-1844-6374)
- Qing Huang (ORCID: https://orcid.org/0000-0001-7083-9416)
- Zhixin Chen
- Lei Qiu (ORCID: https://orcid.org/0000-0003-3843-187X)
- Yang Meng (ORCID: https://orcid.org/0000-0003-2811-6307)
- Xuyang Yang
- Yang Zhang (ORCID: https://orcid.org/0000-0002-4909-4939)
- Bo Zhang (ORCID: https://orcid.org/0000-0003-2962-5314)
- Yaguang Zhang (ORCID: https://orcid.org/0000-0002-9216-1834)
- Zijun Feng
- Ziqiang Wang (ORCID: https://orcid.org/0000-0003-3770-5955)
Institutions
- Chengdu Medical College (CN)
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-11-07
- DOI
- https://doi.org/10.1186/s12967-025-07291-8
- Citations
- 1
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.94