Sexually dimorphic responses in androgen metabolism and signalling in the non-human primate placenta to moderate maternal undernutrition
Differences in placental steroidogenic and angiogenic genes, as well as androgen metabolism and signalling, may explain sex-specific placental responses to MNR. Better understanding of molecular regulators of androgen signalling may lead to novel, targetable therapeutics that improve placental function in complicated pregnancies associated with increased androgen concentrations.
Authors
- Hillary F. Huber (ORCID: https://orcid.org/0000-0001-9734-427X)
- Janna Leigh Morrison (ORCID: https://orcid.org/0000-0002-8602-8519)
- Michael D. Wiese (ORCID: https://orcid.org/0000-0002-3255-9242)
- Ashley S. Meakin (ORCID: https://orcid.org/0000-0003-2806-6274)
- Peter W. Nathanielsz (ORCID: https://orcid.org/0000-0001-8410-6280)
- Vicki Lee Clifton (ORCID: https://orcid.org/0000-0002-4892-6748)
- Cun Li (ORCID: https://orcid.org/0000-0002-0387-9896)
Institutions
- University of Wyoming (US)
- Texas Biomedical Research Institute (US)
- The University of Queensland (AU)
- University of South Australia (AU)
- Mater Research (AU)
Publication Details
- Journal
- Biology of Sex Differences
- Published
- 2025-11-07
- DOI
- https://doi.org/10.1186/s13293-025-00771-y
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00