Long-term outcomes of combination systemic and intravitreal antiviral therapy in the management of acute retinal necrosis

In this long-term cohort of ARN patients, two-thirds of patients in the original study were lost to follow-up leading to reduced sample size, however the loss was equal between the two groups. Given our limited sample size available for follow-up, there is no definitive recommendation for changing the current paradigm of treatment for this disease. Our data suggests that long-term follow-up is required for patients with ARN following their initial treatment. We recommend further studies to provide definitive recommendations in this complex patient group.