Causal association between rheumatoid arthritis and pancreatic cancer: a bidirectional two-sample Mendelian randomization study

Our results support a unidirectional causal relationship, identifying RA as a potential risk factor for the development of pancreatic cancer, with no evidence for a reverse causal effect.

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Publication Details

Journal
Discover Oncology
Published
2025-11-07
DOI
https://doi.org/10.1007/s12672-025-03919-9
Primary Topic
Genetic Associations and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Causal association between rheumatoid arthritis and pancreatic cancer: a bidirectional two-sample Mendelian randomization study

Hua Hao, Lingyu Fu, J. Shiansong Li
Discover Oncology
Genetic Associations and Epidemiology
article

Causal association between rheumatoid arthritis and pancreatic cancer: a bidirectional two-sample Mendelian randomization study

Hua Hao, Lingyu Fu, J. Shiansong Li
article en

Abstract

Our results support a unidirectional causal relationship, identifying RA as a potential risk factor for the development of pancreatic cancer, with no evidence for a reverse causal effect.

Discover OncologyVol. 16(1)
Jiangxi Provincial People's Hospital (CN), The Affiliated Yongchuan Hospital of Chongqing Medical University (CN), Sichuan Provincial Hospital of Traditional Chinese Medicine (CN), Qujiang People's Hospital (CN), Chongqing Medical University (CN)
Openalex Percentile: Top 65%
Genetic Associations and Epidemiology
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