Identification and validation of key genes related to apoptosis in multiple organ dysfunction syndrome
S100A9, S100A8, and BCL2A1 were the key genes of MODS in terms of apoptosis. The constructed nomogram had an excellent predictive value. It offers a novel approach and potential targeted therapy for the clinical diagnosis and treatment of MODS.
Authors
- Huiping Sun (ORCID: https://orcid.org/0000-0002-1353-9916)
- Yanxiao Li (ORCID: https://orcid.org/0000-0002-0600-8711)
- Jian Zhang (ORCID: https://orcid.org/0009-0008-7807-3492)
- Zhi‐Ying Wen
- Yizhou Zheng (ORCID: https://orcid.org/0000-0001-5939-7549)
Institutions
- Xinjiang Medical University (CN)
- First Affiliated Hospital of Xinjiang Medical University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-11-07
- DOI
- https://doi.org/10.1186/s40001-025-03292-x
- Primary Topic
- S100 Proteins and Annexins
- Type
- article
- Field-Weighted Citation Impact
- 0.00