KDM3B suppresses castration-resistance prostate cancer cell proliferation by promoting PTEN expression
The findings suggest that KDM3B suppresses CRPC cell proliferation by enhancing PTEN expression, highlighting its potential role as a tumor-suppressive factor in PCa.
Authors
- Yuntao Wu (ORCID: https://orcid.org/0000-0002-9547-3278)
- Liangming Pan (ORCID: https://orcid.org/0000-0002-7789-7739)
- Xi Chen (ORCID: https://orcid.org/0000-0002-5807-4219)
- Yifan Liu (ORCID: https://orcid.org/0000-0002-3378-8469)
- Pengfei Zhang (ORCID: https://orcid.org/0000-0001-8048-425X)
- Junjie Ma (ORCID: https://orcid.org/0000-0002-8847-3093)
Institutions
- Tongji University (CN)
- Jiading District Central Hospital (CN)
- Jiaxing University (CN)
- Tongji Hospital (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-11-07
- DOI
- https://doi.org/10.1186/s40001-025-03371-z
- Citations
- 1
- Primary Topic
- PI3K/AKT/mTOR signaling in cancer
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China