MPOX outbreak in Africa: the urgent need for local manufacturing of the vaccine and decolonized health systems

Addressing MPOX and future health threats in Africa demands a shift toward decolonized health systems that emphasize South-South collaboration, indigenous knowledge, and local ownership. Strategic interventions, such as regulatory harmonization, equitable technology transfer, and capacity-building, are essential to reduce external dependency. Coordinated short-term actions and long-term investments are crucial for fostering resilient, self-sustaining health systems that can respond effectively to emerging infectious diseases.