Research on E3 ubiquitin ligase TRIM22 knockdown regulating macrophage polarization and osteoclast differentiation through the NF-κB/MAPK pathway
These results reveal a critical mechanism for OC differentiation which is mediated by the TRIM22/NF-κB/MAPK signaling, highlighting a possible avenue for further exploration of target molecules in bone diseases.
Authors
- Yue Wu (ORCID: https://orcid.org/0000-0002-3121-5405)
- Liang Wen (ORCID: https://orcid.org/0000-0001-5967-5596)
- Chao Tang (ORCID: https://orcid.org/0000-0002-5072-5849)
Institutions
- Capital Medical University (CN)
- Huzhou Central Hospital (CN)
- University of South China (CN)
Publication Details
- Journal
- Connective Tissue Research
- Published
- 2025-11-07
- DOI
- https://doi.org/10.1080/03008207.2025.2582833
- Citations
- 1
- Primary Topic
- Bone Metabolism and Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.81