Mathematical modeling predicts novel mechanisms of stream confinement from Trail/Colec12/Dan in the collective migration of cranial neural crest cells
Our work highlights the importance of Trail, Colec12, and Dan in CNCC migration and predicts novel mechanisms for the confinement of CNCCs to stereotypical pathways in vivo.
Authors
- Paul M. Kulesa (ORCID: https://orcid.org/0000-0001-6354-9904)
- Philip K. Maini (ORCID: https://orcid.org/0000-0002-0146-9164)
- Ruth E. Baker (ORCID: https://orcid.org/0000-0002-6304-9333)
- Sam Johnson (ORCID: https://orcid.org/0009-0003-9801-8056)
Institutions
- Children's Mercy Hospital (US)
- University of Oxford (GB)
- Mathematical Institute of the Slovak Academy of Sciences (SK)
- Mercy Hospital (US)
- Mercy Research (US)
Publication Details
- Journal
- Developmental Dynamics
- Published
- 2025-11-07
- DOI
- https://doi.org/10.1002/dvdy.70072
- Citations
- 2
- Primary Topic
- Developmental Biology and Gene Regulation
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- University of Oxford
- Directorate for Biological Sciences
- Biotechnology and Biological Sciences Research Council