Risk factors, stroke rates and aspirin prescribing trends in the Canadian Fabry disease initiative cohort

There was a high incidence of stroke/TIA in the younger CFDI cohort compared to the general Canadian population, despite low levels of traditional vascular risk factors as represented in 10-year estimated ASCVD risk. Primary prevention use of ASA has declined.

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Publication Details

Journal
Orphanet Journal of Rare Diseases
Published
2025-11-07
DOI
https://doi.org/10.1186/s13023-025-04098-0
Primary Topic
Lysosomal Storage Disorders Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Risk factors, stroke rates and aspirin prescribing trends in the Canadian Fabry disease initiative cohort

Lily Zhou, Darwin F. Yeung, Rebecca Robichaud, Anita C. Thomas et al.
Orphanet Journal of Rare Diseases
Lysosomal Storage Disorders Research
article

Risk factors, stroke rates and aspirin prescribing trends in the Canadian Fabry disease initiative cohort

Lily Zhou, Darwin F. Yeung, Rebecca Robichaud, Anita C. Thomas, Caroline Selvage, Anna Lehman, Michael L. West, Emilie T. Théberge, Sandra Sirrs, Kaye LeMoine
article en

Abstract

There was a high incidence of stroke/TIA in the younger CFDI cohort compared to the general Canadian population, despite low levels of traditional vascular risk factors as represented in 10-year estimated ASCVD risk. Primary prevention use of ASA has declined.

Orphanet Journal of Rare DiseasesVol. 20(1)
Dalhousie University (CA), University of British Columbia (CA), Nova Scotia Health Authority (CA), Vancouver General Hospital (CA), Stornoway Diamond (Canada) (CA)
Openalex Percentile: Top 59%
Lysosomal Storage Disorders Research
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Risk factors, stroke rates and aspirin prescribing trends in the Canadian Fabry disease initiative cohort — Lily Zhou, Darwin F. Yeung, et al. · Orphanet Journal of Rare Diseases (2025) | TGRS Research Map | TGRS