Unraveling the Genetic Links: The Impacts of Antidiabetic Drugs on Stroke Risk
Our findings suggest that SGLT2 inhibitors and sulfonylureas may influence the risk of AIS. Additionally, activation of the insulin receptor may reduce the risk of LAS. These results increase our understanding of medication options for stroke patients who require hypoglycemic agents and provide a basis for the strategic repurposing of antidiabetic drugs.
Authors
- Jie Chen (ORCID: https://orcid.org/0000-0002-4029-4192)
- Liucheng Li (ORCID: https://orcid.org/0000-0002-2511-0156)
- Jiadong Xu (ORCID: https://orcid.org/0009-0005-0463-9199)
- Yuzhen Wang (ORCID: https://orcid.org/0009-0005-0535-6852)
Institutions
- Zhejiang Chinese Medical University (CN)
- Sir Run Run Shaw Hospital (CN)
Publication Details
- Journal
- Reviews in Cardiovascular Medicine
- Published
- 2025-10-23
- DOI
- https://doi.org/10.31083/rcm40051
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Zhejiang Province