Protein intake and transitions between frailty states in middle-aged and older adults: a multi-state transition model in the UK Biobank
Higher protein intake moderately reduced the risk for frailty incidence and may have increased the likelihood of recovery from pre-frailty in a dose-dependent manner in middle-aged and older adults. These findings may optimize strategies to prevent frailty in middle-aged and older adults and inform dietary protein guidelines in this population.
Authors
- Nuno Mendonça (ORCID: https://orcid.org/0000-0001-7589-9901)
- Ana Rita Henriques (ORCID: https://orcid.org/0000-0003-4581-0843)
- Armando Raimundo (ORCID: https://orcid.org/0000-0001-9753-8381)
- Helena Canhão (ORCID: https://orcid.org/0000-0003-1894-4870)
- Ana Maria Rodrigues (ORCID: https://orcid.org/0000-0003-2046-8017)
- Carlos Celis‐Morales (ORCID: https://orcid.org/0000-0003-2612-3917)
Institutions
- University of Évora (PT)
- Catholic University of the Maule (CL)
- Lusíada University of Lisbon (PT)
- Administração Regional de Saúde de Lisboa e Vale do Tejo (PT)
- Hospital Santo António dos Capuchos (PT)
- University of Glasgow (GB)
- Universidade Nova de Lisboa (PT)
- Arturo Prat University (CL)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-11-07
- DOI
- https://doi.org/10.1186/s12916-025-04397-0
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fundação para a Ciência e a Tecnologia